Indian Journal of Clinical and Experimental Ophthalmology

Print ISSN: 2395-1443

Online ISSN: 2395-1451

CODEN : IJCEKF

Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is open access, a peer-reviewed medical journal, published quarterly, online, and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fulfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) to its content, which is likely to attract more readers and citations of articles published in IJCEO. Manuscripts must be prepared in more...

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Original Article


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61-65


Authors Details

Amitha Sunny, C V Anthrayose*, Monsy Thomas Mathai, Rakendu Puthiyedathu, Praveena S Kumar


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Effectiveness of treatment by laser or intravitreal anti-vegf-bevacizumab or combination therapy (both Laser and Anti-VEGF) in diabetic macular edema


Original Article

Author Details : Amitha Sunny, C V Anthrayose*, Monsy Thomas Mathai, Rakendu Puthiyedathu, Praveena S Kumar

Volume : 8, Issue : 1, Year : 2022

Article Page : 61-65

https://doi.org/10.18231/j.ijceo.2022.012



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Abstract

Aim: This study aimed to determine the effectiveness of treatment by laser or Intravitreal anti VEGF- Bevacizumab (IVB) or combined therapy (both laser and anti-VEGF) in diabetic macular edema (DME).
Materials and Methods: A prospective observational study in which 90 eyes with diabetic macular edema (DME) were enrolled. According to patient compliance, they were divided in to 3 groups where there was 30 eyes in each group. Patients with DME who were treated with laser were observed (group A). Patients with DME who were treated with Intravitreal Bevacizuamb (IVB) were observed (group B).Patients with DME who were treated with both IVB and Laser were observed (group C). All patients underwent complete ophthalmic examination at baseline and at one and three months after treatment. The outcome measures were changes in Central macular thickness(CMT) and best corrected visual acuity(BCVA). A P value less than 0.05 considered statistically significant.
Results: One month after treatment, Group B showed more statistically significant reduction in CMT and improvement in BCVA than group A and group C(P<0> Conclusions: Combined therapy with IVB and laser appeared to be superior to Laser alone or IVB alone in reducing macular thickness and improving visual acuity. Thus combined therapy can be considered as most effective treatment in DME.
 

Keywords: Diabetic macular edema, Laser photoagulation, IVB, Combined therapy


How to cite : Sunny A, Anthrayose C V, Mathai M T, Puthiyedathu R, Kumar P S, Effectiveness of treatment by laser or intravitreal anti-vegf-bevacizumab or combination therapy (both Laser and Anti-VEGF) in diabetic macular edema. Indian J Clin Exp Ophthalmol 2022;8(1):61-65

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