Indian Journal of Clinical and Experimental Ophthalmology (IJCEO) is an open access, peer-reviewed medical journal, published quarterly, online and in print, by the Innovative Education and Scientific Research Foundation (IESRF) since 2015. To fullfil our aim of rapid dissemination of knowledge, we publish articles ‘Ahead of Print’ on acceptance. In addition, the journal allows free access (Open Access) of its content, which is likely to attract more readers and citations more...
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Volume : 6, Issue : 1, Year : 2020
Article Page : 114-116
Aim: To evaluate the effect of the various phases of menstrual cycle on corneal pachymetry.
Materials and Methods: 100 female participants were selected retrospectively, who underwent a through
screening and ophthalmic evaluation. Corneal pachymetry was measured using an ultrasound pachymeter.
Readings of both the eyes were taken on day 1-3, day 13-15 and day 26-28 of the menstrual cycle. An
intergroup comparison was carried out and statistical significance was found.
Results: It was found that the corneal thickness was at its thickest i.e. 547.51 31.824 on day 13-15 which
coincides with ovulation and thinnest i.e. 548.25 29.948on day 1-3 of the menstrual cycle (p<0> Conclusion: All in all, we conclude that hormonal changes do affect the ocular structures in a profound
manner. In view of the cornea, they have a role in disturbing the pump mechanism of corneal endothelium,
especially when oestrogen levels are at their highest. This eventually leads to a physiological increase in
corneal thickness due to corneal edema and having an indirect effect on visual acuity and corneal sensitivity
and intraocular measurement.
Keywords: Cornea, Pachymetry, Oestrogen, Menstrual cycle.
How to cite : Vyas A K, Rana P, Kothari R N, Patel Z , Soni A, A retrospective study: impact of various phases of menstrual cycle on corneal pachymetry. Indian J Clin Exp Ophthalmol 2020;6(1):114-116
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